IBD
INCLUSION BODY DISEASE
Signs of infection in boas include central nervous system disorders such as paralysis, being unable to right itself when turned over, "star-gazing", inability to strike or constrict. Other signs include chronic regurgitation, extreme weight loss, respiratory infections, and dysecdysis due to the inability to control body movements enough to rub off the old skin. The disease is rapidly fatal in young and juvenile boas, typified by rapid onset of flaccid paralysis.
In pythons, the disease progresses much more rapidly than in boas. Along with the above symptoms (excluding the chronic regurgitation), pythons also tend toward infectious stomatitis ("mouth rot"

, heightened or exaggerated reflex responses, disorientation (which may be precipitated by the onset of central blindness) and loss of motor coordination.
What causes this disease? Intracytoplasmic eosinophilic inclusion bodies have been identified in the epithelial cells of the kidneys and pancreas. Neuronal degeneration and lesions form in the spinal cord and brain, and may be accompanied by myelin degeneration and nerve damage. Damage to the spleen is also found, with that organ being grossly atrophied and fibrosed. Electron microscopy has found that the organism falls into the retrovirus category.
rottie
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